Wilson M Roy

Nassiri Nariman, Wilson M Roy

This review found targeted glaucoma screening in high-risk Black and Hispanic populations is useful and cost-effective, especially leveraging new technologies to improve access and case-finding.

Kitayama Ken, Wilson M Roy

This review highlights Black individuals' consistently higher glaucoma risk, driven by complex genetic and social factors, emphasizing the need for more targeted research to achieve health equity despite race's flawed utility.

Tseng Victoria L, Topouzis Fotis, Yu Fei, Keskini Christina, Pappas Theofanis, Founti Panayiota et al.

Frequent salt intake was linked to increased open-angle glaucoma risk in individuals using antihypertensive medications. This suggests dietary salt may impact glaucoma, especially in treated hypertensive patients.

Founti Panayiota, Coleman Anne L, Wilson M Roy, Yu Fei, Harris Alon, Pappas Theofanis et al.

This study found a 12-year open-angle glaucoma incidence of 4.4% in elderly Whites, with pseudoexfoliative glaucoma showing a significantly higher incidence, highlighting its importance for screening.

Dervenis Nikolaos, Harris Alon, Coleman Anne L, Wilson M Roy, Founti Panayiota, Yu Fei et al.

This study found older age, higher IOP, and taller height correlated with lower active retinal capillary density, while migraine was linked to higher density. These insights may help understand disease mechanisms.

Dervenis Nikolaos, Coleman Anne L, Harris Alon, Wilson M Roy, Yu Fei, Anastasopoulos Eleftherios et al.

This study found blood pressure, especially diastolic, significantly impacts retinal vessel diameters in older adults, alongside age, sex, and lifestyle factors, offering insights into ocular and systemic vascular health.

Founti Panayiota, Coleman Anne L, Wilson M Roy, Yu Fei, Anastasopoulos Eleftherios, Harris Alon et al.

This study found 60% of self-reported glaucoma cases in an elderly population were overdiagnosed, often linked to worse vision, family history, or cataract surgery, highlighting a need for accurate diagnosis.

Harris Alon, Topouzis Fotis, Wilson M Roy, Founti Panayiota, Kheradiya Nisha Shah, Anastasopoulos Eleftherios et al.

Antihypertensives were linked to larger optic disc cupping in non-glaucoma patients with lower blood pressure, suggesting medication-induced hypotension rather than specific drug effects influences disc morphology.

Topouzis Fotis, Wilson M Roy, Harris Alon, Founti Panayiota, Yu Fei, Anastasopoulos Eleftherios et al.

This study found low diastolic ocular perfusion pressure is linked to primary open-angle glaucoma, especially in patients on blood pressure medication, suggesting its role in disease risk.

Lerner S Fabian, Singh Kuldev, Susanna Remo, Wilson M Roy, Lee Brian L, Maul Eugenio

Latin American experts largely agreed on glaucoma care, but some diagnostic and treatment approaches differed from US consensus, highlighting regional practice variations.

Topouzis Fotis, Wilson M Roy, Harris Alon, Founti Panayiota, Yu Fei, Anastasopoulos Eleftherios et al.

This study found elevated IOP is a key risk factor for both POAG and PEXG. Vascular diseases and diabetes treatment were uniquely linked to POAG, suggesting distinct pathogenic pathways.

Anastasopoulos Eleftherios, Topouzis Fotis, Wilson M Roy, Harris Alon, Pappas Theofanis, Yu Fei et al.

In a Greek population, pseudoexfoliation (11.9% prevalence) was strongly linked to higher glaucoma rates, optic disc damage, and elevated intraocular pressure, highlighting its significant ocular risk, even with only slightly higher IOP in non-glaucoma cases.

Topouzis Fotis, Harris Alon, Wilson M Roy, Koskosas Archimidis, Founti Panayiota, Yu Fei et al.

This study found pseudoexfoliation significantly increases glaucoma likelihood at the same elevated intraocular pressure (IOP >20 mmHg). This highlights PEX as a critical risk factor, even with moderately high IOP.

Wilson M Roy, Lee Paul P, Weinreb Robert N, Lee Brian L, Singh Kuldev

This study refined a consensus methodology for glaucoma treatment, finding it successfully increased agreement among ophthalmology experts on management statements, enhancing guideline development.

Singh Kuldev, Lee Brian L, Wilson M Roy

Experts achieved high consensus on glaucoma management via a modified RAND method, providing clinical guidance despite limited strong evidence and varied practice patterns.

Topouzis Fotis, Coleman Anne L, Harris Alon, Koskosas Archimidis, Founti Panayiota, Gong Gordon et al.

This study found that undiagnosed glaucoma is common, especially POAG. Lack of recent eye exams and smaller cup-to-disc ratios increased undiagnosed risk, highlighting the need for regular ophthalmologist visits and thorough optic disc evaluation.

Topouzis Fotis, Wilson M Roy, Harris Alon, Anastasopoulos Eleftherios, Yu Fei, Mavroudis Leonidas et al.

This study found open-angle glaucoma affects 3.8-5.5% of older Greeks, with high pseudoexfoliation glaucoma prevalence, suggesting regional differences in OAG burden.

Topouzis Fotis, Coleman Anne L, Harris Alon, Jonescu-Cuypers Christian, Yu Fei, Mavroudis Leonidas et al.

This study found that in non-glaucoma subjects, treated normal diastolic blood pressure was associated with increased optic disk cupping and decreased rim area, highlighting BP's potential role in optic nerve changes.

Topouzis Fotis, Tranos Paris, Koskosas Archimidis, Pappas Theofanis, Anastasopoulos Eleftherios, Dimitrakos Stavros et al.

This study found filtration surgery effectively lowered IOP in end-stage glaucoma without causing sudden visual loss or significant vision/field changes, suggesting it's safe for preserving vision.

Friedman David S, Wilson M Roy, Liebmann Jeffrey M, Fechtner Robert D, Weinreb Robert N

This review identified high IOP, large cup-to-disk ratio, thin corneas, and older age as the strongest glaucoma progression risk factors, aiding personalized patient risk assessment and treatment decisions.

Weinreb Robert N, Friedman David S, Fechtner Robert D, Cioffi George A, Coleman Anne L, Girkin Christopher A et al.

This study modeled ocular hypertension progression to blindness, finding 12-83 patients need treatment over 15 years to prevent one case of unilateral blindness, aiding treatment decisions.

Varma Rohit, Ying-Lai Mei, Francis Brian A, Nguyen Betsy Bao-Thu, Deneen Jennifer, Wilson M Roy et al.

This study found high rates of open-angle glaucoma (4.74%) and ocular hypertension (3.56%) in older Latinos, with 75% undiagnosed, highlighting the need for early screening in this population.

Topouzis Fotis, Coleman Anne L, Yu Fei, Mavroudis Leonidas, Anastasopoulos Eleftherios, Koskosas Archimidis et al.

The 76-suprathreshold visual field test effectively screened for visual field defects in a population, showing high sensitivity with low false negatives, making it useful for large-scale studies.

Wilson M Roy, Drake Michael, Brandt James

Wilson M Roy, Mendis Upali, Paliwal Amit, Haynatzka Vera

This study compared trabeculectomy and Ahmed valve for primary glaucoma. Trabeculectomy achieved lower initial IOPs, but long-term IOPs and success rates were comparable, suggesting similar efficacy over time.