Narayanaswamy Arun

Tun Tin A, Tan Nicholas Y Q, Tan Royston K Y, Syn Yamon Thant, Chan Hiok Hong, Yu Qing Chang et al.

This study linked asymmetrical NTG-OSA to side-sleeping, finding reduced optic nerve head blood flow in the lower eye during side-lying, suggesting a positional role in glaucoma progression.

Narayanaswamy Arun, Thakur Sahil, Nongpiur Monisha E, Schmetterer Leopold, Hong Young-Kwon, Huang Alex S et al.

This review highlights emerging evidence of lymphatic channels in ocular outflow pathways, suggesting a "uveolymphatic" route for aqueous humor. This finding offers new insights into glaucoma pathophysiology and potential therapeutic targets.

Baskaran Mani, Kumar Rajesh S, Friedman David S, Lu Qing-Shu, Wong Hon-Tym, Chew Paul T K et al.

LPI in asymptomatic angle-closure suspects significantly reduced progression to angle closure or glaucoma over 5 years, but the overall progression rate was low.

Huang Olivia S, Seet Li-Fong, Ho Henrietta W, Chu Stephanie W, Narayanaswamy Arun, Perera Shamira A et al.

Glaucoma eyes showed increased iris AQP1/2 and lower aqueous osmolality, suggesting iris involvement in altered fluid dynamics. This indicates common glaucoma pathophysiology.

Narayanaswamy Arun, Baskaran Mani, Tun Tin A, Htoon Hla M, Aung Tin

This study found pharmacological pupil dilation worsened angle closure in 50% of primary angle-closure suspects. Shallower anterior chambers and larger lens vaults were linked to this increased narrowing, highlighting risk factors for dilation-induced angle closure.

Narayanaswamy Arun, Nai Mui Hoon, Nongpiur Monisha E, Htoon Hla Myint, Thomas Anoop, Sangtam Tiakumzuk et al.

This study found primary angle closure glaucoma (PACG) iris is significantly stiffer than normal or primary open angle glaucoma (POAG) iris, suggesting iris biomechanics play a role in angle closure pathogenesis.

Nongpiur Monisha E, Aboobakar Inas F, Baskaran Mani, Narayanaswamy Arun, Sakata Lisandro M, Wu Renyi et al.

This study found smaller baseline angle opening distance and larger lens vault predict incident angle closure in initially open angles, identifying high-risk individuals.

Seet Li-Fong, Narayanaswamy Arun, Finger Sharon N, Htoon Hla M, Nongpiur Monisha E, Toh Li Zhen et al.

Iris gene expression and biometrics differ in PACG vs. POAG. Combining these factors accurately distinguishes glaucoma types, highlighting distinct underlying pathologies.

Narayanaswamy Arun, Baskaran Mani, Perera Shamira A, Nongpiur Monisha E, Htoon Hla M, Tun Tin A et al.

This study found Argon Laser Peripheral Iridoplasty (ALPI) was less effective than prostaglandin eye drops for primary angle-closure glaucoma after laser iridotomy, showing higher failure rates and less IOP reduction.

Narayanaswamy Arun, Leung Christopher K, Istiantoro Donny V, Perera Shamira A, Ho Ching-Lin, Nongpiur Monisha E et al.

SLT effectively lowered IOP in angle-closure glaucoma patients, comparable to prostaglandin drops short-term, but PGA achieved better complete success and fewer additional treatments.

Narayanaswamy Arun, Perera Shamira A, Htoon Hla M, Hoh Sek-Tien, Seah Steve K, Wong Tina T et al.

This study compared Ologen vs. Mitomycin C in phacotrabeculectomy. Ologen was less effective at lowering eye pressure and required more bleb needling than Mitomycin C, indicating suboptimal performance.

Narayanaswamy Arun, Baskaran Mani, Zheng Yingfeng, Lavanya Raghavan, Wu Renyi, Wong Wan-Ling et al.

This study found glaucoma affects 1.95% of urban Singaporean Indians, with primary open-angle glaucoma being most common. This prevalence is lower than other local Asian groups, informing targeted screening and public health strategies.

Narayanaswamy Arun, Zheng Ce, Perera Shamira A, Htoon Hla M, Friedman David S, Tun Tin A et al.

This study found iris volume decreased with pupil dilation in chronic angle closure, but not in fellow eyes of acute angle closure. These differing iris responses may influence angle closure subtype development.

Zheng Ce, Cheung Carol Y, Aung Tin, Narayanaswamy Arun, Ong Sim-Heng, Friedman David S et al.

AS-OCT revealed angle closure eyes have reduced iris stretch and increased iris bulging during pupil constriction, indicating a distinct mechanism that contributes to angle closure.

Zheng Ce, Cheung Carol Y, Narayanaswamy Arun, Ong Sim-Heng, Perera Shamira A, Baskaran Mani et al.

Chinese angle-closure eyes showed slower pupil constriction than open-angle eyes, suggesting altered irido-pupillary dynamics contribute to angle closure pathogenesis.

Narayanaswamy Arun, Chung Ronald S, Wu Ren-Yi, Park Judy, Wong Wan-Ling, Saw Seang-Mei et al.

This study found corneal biomechanics (CH/CRF) in Chinese adults are influenced by age, sex, IOP, CCT, and diabetes, providing insights for glaucoma assessment and management.

Khor Wei-Boon, Sakata Lisandro M, Friedman David S, Narayanaswamy Arun, Lavanya Raghavan, Perera Shamira A et al.

This study compared AS-OCT scanning protocols for angle closure detection. Imaging only the inferior quadrant performed best, but its low specificity limits population screening utility.